For some elder android devices, like the OPDS reader app running on, the connection with calibre-web server suddenly broke.
Encountering error of :
java.security.cert.CertPathValidatorException: Trust anchor for certification path not found
Could be fixed by following instructions:
remember to change the email account in acme.sh.env file.
Background information:
LetsEncrypt certificates fails on Android phones running Android 7 or older
https://community.letsencrypt.org/t/letsencrypt-certificates-fails-on-android-phones-running-android-7-or-older/205686